Smith & Nephew Iodosorb Cadexomer Iodine Gel

Features of Iodosorb Gel

• Antimicrobial Properties:
  • The smart release system of Cadexomer Iodine allows Iodosorb gel to provide sustained antimicrobial activity for up to 72 hours.
  • Iodine has a broad antimicrobial spectrum and low kill time at low concentrations.
  • Not only does iodine kill a broad spectrum of microorganisms, but it also does so very rapidly.
• Odor Control:
  • Odor is generated by infected wounds and heavily colonized by anaerobic and aerobic bacteria.
  • Odor is attributed to the volatiles produced by the bacteria within a wound.
  • Therefore, controlling such bacteria also controls the associated odor.
• Desloughing Properties:
  • Wound fluid containing bacteria and cellular debris is readily drawn into the Cadexomer matrix.
  • This cleans the wound bed of extra debris and bacteria, thereby promoting wound healing.
  • Desloughing and removing bacteria from the wound is believed to be responsible for the increase in wound healing and the rate of epithelialization.
• Exudate Control Properties:
  • Cadexomer Iodine manages excess exudate by its ability to absorb up to six times its own weight.
  • This reduces the risk of maceration and leakage.
  • It can result in fewer dressing changes and reduced nursing supervision for patients compared to standard wound management modalities.
• Cadexomer Iodine Safety:
  • Iodosorb has a concentration of 0.9% Cadexomer Iodine.
  • Studies show that at this concentration and complexed to cadexomer, there is no evidence that Iodosorb is toxic.
  • Moreover, the concentration gradient of iodine is formed with the lowest concentration at the wound surface and the greatest concentration away from the wound.

When to use Iodine Gel?

• Infected, traumatic, and surgical wounds
• Treating wet ulcers
• Pressure sores
• Diabetic foot ulcers
• Venous Stasis Ulcers

When not to use Cadexomer Gel?

• Iodine sensitivity
• Hashimoto's thyroiditis
• Non-toxic nodular goiter
• Graves Disease
• Pregnant or lactating women

How does Iodosorb Ointment work?

• Cadexomer Iodine is a uniquely formulated starch matrix formed into spherical, highly absorbent microbeads containing 0.9% elemental iodine.
• The Cadexomer is a 3D cross-linked polysaccharide starch matrix.
• The 0.9% iodine is physically bound to the Cadexomer matrix and only released when required. Wound fluid and exudate are absorbed into the Cadexomer beads of the Cadexomer Iodine, allowing the iodine to be released slowly.
• When Cadexomer Iodine is applied to the wound surface, exudate, pus, and debris are absorbed into the Cadexomer beads.
• The beads will swell, resulting in the formation of a demonstrable gel.
• The presence of exudate and the consequent swelling of the beads results in the cross-linked bonds of the Cadexomer matrix breaking and the iodine being released into the surrounding wound environment.
• When the iodine is released, the amount of iodine released will be to a level such that the concentration of iodine in the dressing and the wound environment reach equilibrium.
• The equilibrium will remain and no further iodine will be released until the balance is disturbed.
• Once the iodine in the surrounding wound environment has been depleted, more will be released from the product until the equilibrium is reached again and will remain until disturbed.
• This process will continue until all the 0.9% iodine within the product has been exhausted.